AIM ImmunoTech Announces Late-Breaking Presentation at the International Conference on Antiviral Research Regarding Ampligen as a Potential Therapy Against Ebola Virus Disease

Growing body of data supports Ampligen’s potential as both a prophylactic and an early-onset therapy against human Ebola virus disease outbreaks

OCALA, Fla., March 16, 2023 (GLOBE NEWSWIRE) — AIM ImmunoTech Inc. (NYSE American: AIM) (“AIM” or the “Company”), an immuno-pharma company focused on the research and development of therapeutics to treat multiple types of cancers, immune disorders, and viral diseases — including COVID-19, the disease caused by the SARS-CoV-2 virus — today announced a late-breaking presentation at the 36th International Conference on Antiviral Research (ICAR) detailing Ampligen’s mechanism of action in the treatment of Ebola virus disease (EVD).

The presentation was given by Angela Corona, PhD, Department of Life and Environmental Sciences, University of Cagliari, Monserrato, Italy, and one of the published authors of a recent manuscript titled “Ebola virus disease: In vivo protection provided by the PAMP restricted TLR3 agonist rintatolimod and its mechanism of action.” Ebola virus (EBOV) is a highly infectious and lethal pathogen responsible for sporadic, self-limiting clusters of EVD in Central Africa capable of reaching epidemic status. Highlights of the recently published Ampligen data that was presented include:

  • As a TLR3 agonist, Ampligen induces and enhances innate immunological responses to EBOV infection.
  • Ampligen appears to inactivate the EBOV lethal factor (EBOV VP35), which is believed to be responsible, in part, for the high mortality rate observed in humans, by acting as a “competitive decoy.” VP35 is understood to sequester the dsRNA produced by EBOV during its replication, which inhibits the normal innate immune responses to viral infection.
  • Ampligen protected mice from a lethal challenge by mouse adapted EBOV-Zaire and its associated weight loss.
  • The 6 mg/kg doses, frequently used in AIM’s clinical trials, used in mouse model is easily achievable and well tolerated in humans.
  • Overall, the data suggest Ampligen’s potential as a viable candidate to protect against exposure to EBOV.

The corresponding slides from the presentation at ICAR are now available on the Company’s website ( on the “Events and Presentations” page.

AIM CEO Thomas K. Equels commented, “In vivo pre-clinical analysis shows that Ampligen has potential as both a prophylactic and an early-onset therapeutic in Ebola virus disease. Animal studies with Ampligen at the United States Army Medical Research Institute of Infectious Diseases Biosafety Level 4 laboratories demonstrated 100% protective survival, as compared to 100% mortality in Ebola virus disease. Those animal studies are indicative of the drug’s high potential for efficacy. The analysis presented at ICAR now provides a clear understanding of why Ampligen is achieving such a high level of efficacy in these animal models, signaling its potential as a human therapy.”

Ampligen has been granted Orphan Drug status for Ebola virus disease by the European Medicines Agency and the FDA. Ampligen is not currently approved for the prevention or treatment of EVD.

The Company intends to file Investigational New Drug applications to study the use of Ampligen (1) as an early onset therapy for the treatment of EBOV, and (2) for the prevention of Ebola virus reactivation. Ultimately, the Company’s goal is to seek a Tropical Disease Priority Review Voucher for new drug applications associated with these indications.

About the International Society for Antiviral Research (ISAR)

The International Society for Antiviral Research (ISAR) is an internationally recognized organization for scientists involved in basic, applied, and clinical aspects of antiviral research. The Society main event is the annual International Conference on Antiviral Research (ICAR), a truly interdisciplinary meeting which attracts the interest of chemists, biologists, and clinicians.

About Ampligen

Ampligen is AIM’s dsRNA product candidate being developed for globally important cancers, viral diseases and disorders of the immune system. Ampligen is currently being evaluated as a combinational therapy for the treatment of a variety of solid tumor types in multiple clinical trials – both underway and planned – at major cancer research centers around the country. Ampligen is being used to treat pancreatic cancer patients in an Early Access Program approved by the Inspectorate of Healthcare in the Netherlands at Erasmus Medical Center. Additionally, Ampligen is also approved in Argentina for the treatment of severe chronic fatigue syndrome and is currently being evaluated in SARS-CoV-2/COVID-19, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Post COVID Conditions.

About AIM ImmunoTech Inc.

AIM ImmunoTech Inc. is an immuno-pharma company focused on the research and development of therapeutics to treat multiple types of cancers, immune disorders, and viral diseases, including COVID-19. The Company’s lead product, an investigational new drug called Ampligen® (rintatolimod) is an immuno-modulator with broad spectrum activity being investigated for globally important cancers, viral diseases and disorders of the immune system.

For more information, please visit and connect with the Company on Twitter, LinkedIn, and Facebook.

Cautionary Statement

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 (the “PSLRA”). Words such as “may,” “will,” “expect,” “plan,” “anticipate” and similar expressions (as well as other words or expressions referencing future events or circumstances) are intended to identify forward-looking statements. Many of these forward-looking statements involve a number of risks and uncertainties. The clinical study and other matters discussed above are subject to a number of unknowns including, but not limited to, that significant additional testing and trials will be required to determine whether Ampligen will be an effective treatment for Ebola virus, comments and additional testing requested by the FDA if and when the Company files the Investigational New Drug application and whether the Company will be able to obtain a Tropical Disease Priority Review Voucher for the new drug application. Among other things, for those statements, the Company claims the protection of safe harbor for forward-looking statements contained in the PSLRA. The Company does not undertake to update any of these forward-looking statements to reflect events or circumstances that occur after the date hereof. Two of the authors of the manuscript are officers or directors of the Company. The information found on our website is not incorporated by reference into this press release and is included for reference purposes only.

Investor Relations Contact
Jenene Thomas

GlobeNewswire Distribution ID 8789385

Play Ball! Major League Baseball and Zoom Announce First-of-its-kind Partnership; Zoom Contact Center to Power ‘Zoom Replay Operations Center’

  • Zoom becomes Official Unified Communications Platform of MLB and Presenting Partner of MLB Replay Review
  • MLB to introduce league-first, broadcast look-ins from the Zoom Replay Operations Center
  • Zoom Contact Center, Zoom Events, and Zoom’s all-in-one collaboration platform will deliver unprecedented transparency to the fans and enhanced communications between front office staff, umpires, and league officials

SAN JOSE, Calif. and NEW YORK, March 16, 2023 (GLOBE NEWSWIRE) — Major League Baseball (MLB) and Zoom Video Communications, Inc. (NASDAQ: ZM) today announced a first-of-its-kind partnership for the league, aimed to enhance MLB games and the fan viewership experience. As the new Official Unified Communications Platform of MLB, Zoom Contact Center and the Zoom platform technology will power new elements of Major League games and broadcasts.

MLB Chief Operations & Strategy Officer Chris Marinak, said: “We are always looking for innovative ways to leverage best-in-class technology to advance the MLB experience and deliver more to our fans. Partnering with Zoom, a category leader that reinvented the way we connect, was a natural next step for us. We are excited to integrate Zoom Contact Center and other Zoom platform technology into our gameday operations and continue to modernize experiences in a secure, reliable, and innovative way.”

Zoom Chief Marketing Officer, Janine Pelosi said: “MLB brings together tens of millions of passionate fans every season. Zoom’s rapid pace of innovation and obsession with making human connection easier and better, is crucial to help MLB evolve its experience and deliver unprecedented transparency and access to its fans. With MLB leveraging Zoom Contact Center and Zoom’s all-in-one collaboration platform, we are able to truly show the world how a historical brand can continue to innovate and unlock new possibilities.”

Zoom platform integration drives MLB innovations:

  • Zoom Contact Center transforms replay review – In the 2022 MLB season, there were more than 1,400 replay reviews. Historically, the league’s replay review was reliant on disparate technology and audio-only communication with umpires on the field, resulting in fans being disconnected from the decision-making process.

    Beginning with the 2023 Season, the Crew Chief, the most senior member of the four-man umpire crew, will connect to the Zoom Replay Operations Center using Zoom’s Contact Center solution during any replay review. During national broadcasts on MLB Network and Apple TV+, fans will also see the Zoom Replay Operations Center in action live during replay reviews and hear from an expert rules analyst who will discuss replay reviews with the broadcast team. MLB’s goal with this new setup is to create a more transparent and engaging review process.

  • Zoom Platform helps streamline communication – Zoom will be used to securely deliver sensitive information in one of the most high-pressure and high-profile MLB Events, Day One of the 2023 MLB Draft.
  • Broader league-wide Zoom integrations advance collaboration – Zoom’s all-in-one collaboration platform is integrated across several MLB clubs, platforms, and broadcast outlets. In addition to Zoom Meetings, many MLB teams are using Zoom Phone to stay connected with colleagues and customers, as well as Zoom Contact Center to deliver prompt, accurate, and highly personalized customer experiences to their fans. MLB’s corporate offices use Zoom Meetings, Zoom Rooms, Zoom Phone, and Zoom Webinar to connect, collaborate, and communicate.

To learn more about the Zoom platform and the technology that will power several new elements in MLB starting in the 2023 season, read the blog here.

About MLB
Major League Baseball (MLB) is the most historic professional sports league in the United States and consists of 30 member clubs in the U.S. and Canada, representing the highest level of professional baseball. Led by Commissioner Robert D. Manfred, Jr., MLB remains committed to making an impact in the communities of the U.S., Canada and throughout the world, perpetuating the sport’s larger role in society and permeating every facet of baseball’s business, marketing, community relations and social responsibility endeavors. MLB currently features record levels of competitive balance, continues to expand its global reach through programming and content to fans all over the world, and registered records in games and minutes watched this season on MLB.TV. With the continued success of MLB Network and MLB digital platforms, MLB continues to find innovative ways for its fans to enjoy America’s National Pastime and a truly global game. For more information on Major League Baseball, visit

About Zoom
Zoom is an all-in-one intelligent collaboration platform that makes connecting easier, more immersive, and more dynamic for businesses and individuals. Zoom technology puts people at the center, enabling meaningful connections, facilitating modern collaboration, and driving human innovation through solutions like team chat, phone, meetings, omnichannel cloud contact center, smart recordings, whiteboard, and more, in one offering. Founded in 2011, Zoom is publicly traded (NASDAQ:ZM) and headquartered in San Jose, California. Get more info at

MLB Communications
David Hochman

Zoom Public Relations
Candace Dean

GlobeNewswire Distribution ID 8789553

Get the expert take on the African tax landscape at IBFD’s Masterclass

IBFD Masterclass: Tax Structuring in Africa – Selected Critical Issues

Masterclass returns to strengthen African taxation


IBFD will host the Masterclass: Tax Structuring in Africa – Selected Critical Issues, on 22-23 May 2023 in Arusha, Tanzania for African tax practitioners. This advanced-level training will provide participants with a platform to learn, share and debate the most pressing issues in international taxation.

African tax professionals such as tax managers and directors, in-house tax and accounting specialists in commerce and industry, practitioners in tax advisory firms, and government officials, will gain a deeper and practical understanding of the most important topics in international taxation, from a unique African perspective.

Which topics will the Masterclass programme cover?

  • Current Issues in International Taxation and Transfer Pricing from Around the Globe – Impact on African Inbound and Outbound Investments
  • Tax Treaty Policy in Africa: Impact of Treaty Anti-Avoidance Rules
  • Artificial Avoidance of Permanent Establishments: Experience from Around the Globe and Potential Lessons for Africa
  • Cross-Border Business Activities in Africa – Cross-Border Services and Withholding Tax Structuring

Find out more and benefit from the early-bird discount!
For more details on the programme objectives, course content, structure, trainers and to benefit from the 10% early-bird discount ending 20 March, visit

Contact information: Phil Windus, Senior Marketing Coordinator:

About IBFD
IBFD is a leading international provider of cross-border tax expertise, with a long-standing history of supporting and contributing to tax research and academic activities. As an independent foundation, IBFD utilizes its global network of tax experts and its Knowledge Centre to serve Fortune 500 companies, governments, international consultancy firms and tax advisers.

A photo accompanying this announcement is available at

GlobeNewswire Distribution ID 8789135

Parents told to exercise patience at vaccination centres

Mr Solomon Antwi Brefo, Ayensuano District Disease Control Officer, Ghana Health Service has advised parents to exercise patience when seeking treatment for their children at vaccination centres. He said children who were not vaccinated earlier due to the nationwide shortage of the childhood vaccines, were at no risk of complications so parents should exhibit patience towards nurses. ‘ Exercising patience is a vital way of improving a sound and a good health care. Every child who is eligible to vaccinate will be immunised,’ he said. Ghana, in the last quarter of 2022 and February 2023, experienced a nationwide shortage of childhood vaccines such as Bacille Calmette-Guérin (BCG) for Tuberculosis (TB), Measles Rubella (MR) and Oral Polio vaccine (OPV). The situation has over the period put parents whose children were due for immunisation in perplexity. This, Mr Kwaku Agyeman Manu, Minister of Health assured that ‘We have done all the necessary arrangements with the United Nations Children’s Fund (UNICEF) and we are doing all things possible to get these vaccines earlier.’ The vaccines have now arrived in the country. According to Dr Patrick Kuma – Aboagye, Director General of the Ghana Health Service, the government had procured stocks that were enough to last beyond this year, but they were being received in batches. Mr Brefo, Ayensuano District Disease Control Officer told the Ghana News that the district had received BCG, Rota, MR and OPV vaccines and distributed them to 29 facilities in the nine sub-districts. He said the district did not record any casualty during the shortage period. The district’s annual target to immunise children under one is 3,940 and the monthly target is 328, he noted.

Source: Ghana News Agency

Ghana Standards Authority, FDA delegation pay Courtesy Call on Rwandan High Commissioner

The Ghana Standards Authority (GSA) and the Food and Drugs Authority (FDA) have paid a joint courtesy call on Dr. Aisa Kimbo Kacyira, High Commissioner of the Republic of Rwanda to Ghana. The visit was to congratulate Dr. Kacyira on her appointment as Head of the United Nations Support Office in Somalia (UNSOS), by United Nations Secretary-General António Guterres. Dr. Kacyira will succeed Lisa Filipetto of Australia. The Director-General of the GSA, Professor Alex Dodoo, and the Chief Executive of the FDA, Mrs. Mimi Delese Darko, led their respective delegations as they held discussions with the High Commissioner. ‘Not only have you brought the GSA and FDA much closer, but you have also forged a similar relationship between the Rwanda FDA and Rwanda Standards Board,’ Prof Dodoo, noted. Prof. Dodoo recalled previous discussions on enhancing trade between the two countries, ‘without necessarily calling it a Mutual Recognition Agreement, but based on what our respective laws say.’ This has become the model, so the African Standards Organisation, has stopped calling for a Mutual Recognition Agreement, but rather a Framework. Prof. Dodoo said countries needed to get their regulators and standards authorities together to enable them to figure out a way to work things out effectively. A discussion between GSA, FDA, and Rwanda’s High Commissioner mainly propelled this development. So, having a framework within which countries collaborate, bilaterally or multilaterally, has been adopted and has become a guiding principle, thanks to Dr. Kacyira, Prof said. Mrs. Mimi Darko, Chief Executive of FDA, also expressed her excitement in working hand-in-hand with the Commissioner and thanked her for the continuous support. Mrs. Mimi Darko took the opportunity to congratulate H.E. Dr. Kacyira on her appointment as Head of United Nations Support Office in Somalia and also acknowledged the fact that it was the first time an African had been given the job. ‘From what you have done, you deserve to go higher to do bigger things. So it is by the grace of God that you have got this position and I think for where you’re going, you’re going to do more excellent things.’ Speaking on working with Rwanda, she said, ‘We collaborated with Rwanda and they were recently Benchmarked and for first timer to had very little to do to attain Maturity Level 3 and that is very impressive.’ ‘We are looking forward to move within the AfCFTA and we want the Ghana-Rwanda trade to be the strongest and the best in the continent. ‘ ‘From the first time we met, your zeal to ensure that collaborations between our countries moved and the passion with which you wanted it to happen was amazing.’ Dr. Kacyira welcomed her guests and expressed joy about the ongoing harmonisation between GSA and FDA, to boost intra-african trade in the wake of AfCFTA. ‘I felt a real sense of belonging when I got to Ghana. The Pan-Africanism which is at play here is real, and that has enabled us to establish ourselves to showcase to the world that Africa, Ghana, and Rwanda don’t have a choice but to lead Africa,’ Dr. Kacyira reiterated. The discussions held during the courtesy call will fuel many future collaborations between Ghana and Rwanda through trade and development. Among the GSA delegation are Prof Dodoo, Director-General, Jessica Nkansah, the Acting Director, Inspectorate Division, Nina Amoah Buabeng, Programme Development Coordinator and Kofi Yeboah Debrah of the PR Department. The FDA delegation included Mrs. Mimi Darko, CEO, Rhoda Appiah, Head of Communications, Kwame Dei Asamoah-Okyere, Director Business Development and International Partnership and Mrs. Yvonne Nkrumah DCEO (Deputy CEO) Corporate Services. According to the United Nations, Ms. Kacyira brings to this position more than 30 years of experience in a multi-faceted career in diplomacy and community and political engagement, as well as in leadership in development and humanitarian assistance, at local, national and international levels. Since 2020, Dr. Kacyira has served as the resident High Commissioner to the Government of Ghana and non-resident representative to Benin, Togo, Sierra Leone, Côte d’Ivoire and Liberia. Prior to that, she served as Governor of the Eastern Province (2011), Rwanda’s largest province, and as Executive Mayor of Kigali (2006-2011). Between 2003 and 2006, she served as a Member of Parliament and actively participated in Parliament’s legislative and oversight functions, in addition to community mobilization. In addition to her political and diplomatic roles, Ms. Kacyira has held several positions in development and humanitarian assistance, notably as Deputy Executive Director with the United Nations Human Settlements Programme (UN-Habitat) from 2011 to 2018, and also in programme and project management with the Ministry of Agriculture in Rwanda, as well as various NGOs, including Oxfam and Care International. The United Nations Support Office in Somalia (UNSOS) has a core mission to provide critical support to AMISOM, UNISOM, and the Somalian Security Forces to make them more effective in supporting Somalia’s peace and stability efforts.

Source: Ghana News Agency

Tema ‘White House’ rots away while decentralized departments have no offices

The ‘White House’, one of the iconic buildings in Tema, is rotting away and needs urgent refurbishment to provide office accommodation for the various decentralized departments under the Tema West Municipal Assembly (TWMA). The two-story building which looks solid and attractive from afar has not seen any major renovation works since its construction many years ago. Checks from the Tema Metropolitan Assembly (TMA), the mother assembly of the TWMA revealed that Tema ‘White House’ was named after the USA White House to mimic its importance and power when the revolutionary officers hijacked it after it was built to house the TMA in the early 1980s. Mr. Frank Asante, Tema Metropolitan Public Relations Officer told the Ghana News Agency that, the building was constructed to house the TMA, as part of the Tema Ministry Enclave. He said the area also has the offices of the Ghana National Fire Service (GNFS), Audit Service, Labour, Rent Control, Health Directorate, Ghana Revenue Authority, Environmental Protection Agency, and Agric Department among others. Mr. Asante added that however during the coup in 1981, the revolutionary officers took over the building and used it for their activities including the summons, and adjudications. He said with that, Nii Armarh Ashitey, opted for the construction of the current office of TMA at the business central area to house the Assembly, making decentralized departments to occupy it after the officers vacated it. In 2010, the then Tema Metropolitan Security Council (MESEC) toured the building and took the decision to relocate the Electoral Commission, and the Tema Magistrate Court from the second floor which had serious structural cracks with the concrete ceiling falling off on workers. Thirteen years after, when the Ghana News Agency visited the ‘White House’ which is now under the TWMA, it was observed that even though the first and second floors have been vacated, the ground floor still houses the Tema Metro offices of the National Service Secretariat, Non-Formal Education, and Co-operative Department. Two of the offices have also been recently painted ready to house the Tema West Office of the Commission on Human Rights and Administrative Justice (CHRAJ). Climbing to the first and second floors of the ‘white house’, revealed that there were deep structural cracks, with fungal-infested walls. Deep holes have been created in the ceiling as the concrete has fallen off over the long years of non-maintenance, the iron rods holding the concrete roofs, were exposed and rusty an indication of corrosion due to contact with water coming from leakages from the roof. One of the offices have household items with the door locked with a small padlock, the GNA gathered that a woman who was ejected from her room around the area took over the place and was using it as a home. Yousif, a Burkinabe haulage truck driver’s mate, the GNA spotted charging his phone in one of the most affected rooms which used to house the Magistrate Court, said the woman often went out in the morning and returned at night to sleep. Ms. Afia Mansa, a food vendor operating on the compound of the ‘white house’, said she was the unofficial caretaker of the building as she updated officials of the TWMA whenever they visited the place on the happenings there. Ms. Mansa said day in and day out people came around to look at the possibility of renting the place. Meanwhile, checks at TMWA revealed that the engineers recently visited the ‘white house’ and preparing to renovate it.

Source: Ghana News Agency

Military brutality unconstitutional, officers must be tried – OccupyGhana

OccupyGhana says all military personnel involved in the brutalities at Ashaiman following the murder of the soldier, Imoro Sheriff, must face the law. In a press statement, the Pressure Group, described the actions of the Military as ‘barbaric, totally uncalled for, absolutely unconstitutional and unlawful’. OccupyGhana said the constitution guaranteed inviolable dignity to all Ghanaians, even if suspected to have committed a crime and that no Ghanaian should be subjected to ‘torture or other cruel, inhuman or degrading treatment or punishment or any other condition that detracts or is likely to detract from [our] dignity and worth as human beings’. It has, therefore, stated that as the accused persons faced the law, the Military personnel involved and any officer who authorised those actions against residents of Ashaiman must be tried, and officers and supervisors who endorsed the acts after they happened must also resign. OccupyGhana also asked the Military High Command to apologise to everyone subjected to violations and that the State needed to compensate affected persons. ‘There is, therefore, no justification for the pain, suffering and torture that the soldiers visited on clearly innocent people… Any powers of arrest that the Military may claim to have, is no different from the arrest powers of any citizen of this country, as regulated by the Constitution. ‘ It said the rights of Ashaiman residents had been gravely violated as the Military itself appeared to have filmed and shared videos as they subjected citizens to ‘unspeakable indignities, making an absolute and total a farce of what our Constitution represents and what they see their role in the Ghanaian society as. With these barbaric acts, they made themselves, judge, jury and executioner, and a very terrible one at that!’ ‘The Constitution demands ‘reasonable suspicion’ that the specific person arrested has committed an offence. A mass swoop that occurs days after an offence, and detains as many as 184 people cannot be based on any suspicion that each of them had committed the offence. And even if any such suspicion arguably existed, it would be grossly unreasonable, unwarranted and perverse. Thus, the military unjustifiably violated the constitutional right to due process of every person they detained,’ the statement noted. It said the press statement issued by the Department of Public Relations of the Military on March 7, 2023, was an ‘absurd justification’ of the actions of the officers and had been exposed by the facts provided by the police as false on March 12, 2023, that the unfortunate death resulted from a suspected robbery attempt. The Pressure Group also said the suspected robbery could have happened in any part of the country and to any citizen and that the Military would not have intervened. OccupyGhana asked the Military to acknowledge its mandate as all other security agencies to protect the people of Ghana and not to turn on them. It extended its condolences to the family and loved ones of the murdered military officer.

Source: Ghana News Agency

New Kejetia market temporary closed down

The Ashanti Regional Coordinating Council (ARCC) has ordered the temporary closure of the new Kejetia market in Kumasi following Wednesday’s fire outbreak in some parts of the market. The Council has also set up a committee to investigate the cause of the fire outbreak and recommend measures to prevent future occurrences. Mr Simon Osei Mensah, Ashanti Regional Minister, announced this after touring the market to inspect the damages caused by the fire. The fire outbreak which was said to have started around 16:30 hours on Wednesday afternoon, affected many shops and destroyed merchandised worth millions of Ghana cedis. Mr Osei Mensah, who is also the chairman of the Regional Security Council, was accompanied by officials from the Ghana National Fire Service, the National Disaster Management Organization (NADMO), the Police and the Kumasi metropolitan assembly. Mr Osei Mensah, expressed worry about the extent of damage caused by the fire and said the Committee would work to identify all the challenges in the market and recommend effective measures to address them. He called on the affected traders to remain calm as the authorities work to find appropriate solutions to the problems. Mr Henry Giwah, Ashanti Regional Fire Commander, said the Service had launched investigations to ascertain the cause of the fire in the market. He said the installed fire equipment at the market were not compatible with that of the Ghana National Fire Service, and that posed as a challenge in the fight to control the fire.

Source: Ghana News Agency