Centrient Pharmaceuticals boosting statins API manufacturing capacity

Rotterdam, The Netherlands, June 21, 2021 (GLOBE NEWSWIRE) —

Summary:

  • Centrient Pharmaceuticals has started production at its newly built statins API manufacturing unit in Toansa, India.
  • With this expansion the company is doubling its production capacity of Atorvastatin and Rosuvastatin, meeting the increased demand for its high-quality uniquely produced statins.
  • Centrient Pharmaceuticals’ statins are one of the most sustainably produced in the industry by eliminating harmful solvents, generating less waste, and a reduced carbon footprint of 32% as compared to traditional manufacturers.
  • Using backward integrated manufacturing methods, and dedicated production facilities, Centrient Pharmaceuticals is able to offer its customers security of supply.

Centrient Pharmaceuticals (“Centrient”), the global leader in sustainable antibiotics, next-generation statins and anti-fungals, announced today to have started production at its new statins manufacturing unit. With the building of its second dedicated unit on the Toansa site in India now completed, the company will double its statins production capacity. This will enable Centrient to meet growing demand for its sustainably manufactured Atorvastatin and Rosuvastatin Active Pharmaceutical Ingredients (APIs).

Statins are currently the most prescribed drug class globally for the treatment of high cholesterol and cardiovascular diseases and are among the top-selling drugs worldwide. The markets for Atorvastatin and Rosuvastatin in particular, has shown steady growth in the past years, as a result of the continued global prevalence of high cholesterol issues, replacement of older generation statins, and genericization of the market.

Starting almost a decade ago, Centrient has grown today into one of the leading statin API suppliers worldwide, servicing large pharma companies around the globe.

Next to high-quality features like long shelf life and large batch sizes, the company offers security of supply to customers through its dedicated statins production facility and backward integration. Being backward integrated, Centrient is independent from external imports of starting materials. Its enzymatic route of synthesis and patented technology minimise the use of harmful solvents, generate less waste, and reduce the company’s carbon footprint by 32% as compared to traditional manufacturers.

The news of the facility expansion follows major milestones on statins that the company reached in the past years. In 2012, under the name of DSM Sinochem Pharmaceuticals, it was the first pharmaceutical manufacturer worldwide to offer generic Atorvastatin APIs under a Certificate of Suitability to the Monograph of the European Pharmacopoeia (CEP). Since 2014, it has produced the unique Atorvastatin APIs in its state-of-the-art facility in Toansa, India for third-party customers.

In addition, the company was one of the first three companies worldwide that started to offer generic Rosuvastatin APIs under CEP in 2016. Two years later, the first generic Rosuvastatin and Atorvastatin finished dosage forms were launched in Western Europe.

“With the doubling of our production capacity, we demonstrate our commitment to maintain our leadership position in line with our strategy and to continue supporting our customers’ business growth. Guided by our brand promise of Quality, Reliability, and Sustainability, Centrient’s Rosuvastatin and Atorvastatin offer superior performance in all three areas to the benefit of our customers and the environment.”, says Frans Vlaar, Chief Commercial Officer at Centrient.

Ground breaking of the new manufacturing unit started at the end of 2019 and commercial supplies from the new unit will start in mid-2021With the new manufacturing line being operational and doubling the production capacity, Centrient will be even better positioned to secure supply, meeting the growing demand from customers and helping to improve the lives of patients who are in need of these medicine.

“We are extremely proud that we have been able to complete this project in a timely way given the challenges of executing such a complex project in the midst of the COVID pandemic,” says Jim McPherson, Chief Quality & Technical Operations Officer. “It reinforces our absolute commitment to meet the expectations of our customers as a partner of choice – delivering reliable and secure supply using leading sustainable technologies. The facility incorporates design features that allow further improvements in GMP and energy utilization, and enable greater automation for improved process control.”

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About Centrient Pharmaceuticals

Centrient Pharmaceuticals is the leading manufacturer of beta-lactam antibiotics, and a provider of next generation statins and antifungals. We produce and sell intermediates, active pharmaceutical ingredients and finished dosage forms.

We stand proudly at the centre of modern healthcare, as a maker of essential and life-saving medicines. With our commitment to Quality, Reliability and Sustainability at the heart of everything we do, our over 2200 employees work continuously to meet our customers’ needs. We work towards a sustainable future by actively participating in the fight against antimicrobial resistance.

Founded 150 years ago as the ‘Nederlandsche Gist- en Spiritusfabriek’, our company was known as Gist Brocades and more recently DSM Sinochem Pharmaceuticals. Headquartered in Rotterdam (Netherlands), we have production facilities and sales offices in China, India, the Netherlands, Spain, Egypt, the United States and Mexico. Centrient Pharmaceuticals is wholly owned by Bain Capital Private Equity, a leading global private investment firm.

For more information please visit www.centrient.com or contact Centrient Pharmaceuticals Corporate Communications, Alice Beijersbergen, Director Branding & Communications. E-Mail: alice.beijersbergen@centrient.com.

Forward-looking statements
This press release may contain forward-looking statements with respect to Centrient Pharmaceuticals’ future financial performance and position. Such statements are based on current expectations, estimates and projections of Centrient and information currently available to the company. Centrient cautions readers that such statements involve certain risks and uncertainties that are difficult to predict and therefore it should be understood that many factors can cause actual performance and position to differ materially from these statements. Centrient has no obligation to update the statements contained in this press release, unless required by law. The English language version of the press release is governing.

Alice Beijersbergen
Centrient Pharmaceuticals
alice.beijersbergen@centrient.com

JinkoSolar delivers initial DC-coupled storage system to West Africa

SHANGHAI, June 21, 2021 /PRNewswire/ — JinkoSolar Holding Co., Ltd. (the “Company” or “JinkoSolar”) (NYSE: JKS), one the largest and most innovative solar module manufacturers, today announced to deliver 1.2MWh of energy storage system to West Africa. JinkoSolar’s experience in solar, storage, complex multi-application systems resulted in offering a new solution in African market: integrating batteries, Power Conditioning System (PCS), DC modular, switch cabinets, with EMS software. This all-in-one, fully integrated modular and compact solution minimizes complexity of deployment activities, and delivers the lowest lifecycle costs.

JinkoSolar Energy Storage Project in West Africa

JinkoSolar’s DC coupled battery storage system can meet project requirements of varying scale and is suitable for various environmental conditions, making it an ideal solution for grid ancillary services and C&I applications while ensuring reliability and safety. The potential advantage of this DC coupled solution Includes improved system efficiency, lower balance of plant costs, and clipped solar recapture. With storage attached to the solar system, the batteries can be charged with excess solar generation when the PV reaches its peak and would otherwise begin clipping. The stored energy can be introduced into the grid at the appropriate time, maximizing the value of the system’s generation. The flexibility and broad capabilities of the EMS software enable effective and efficient control and management over the entire system, compatible with solar, wind, grid, and diesel engines.

“For us, this is a milestone project of delivering ESS system to Africa.  It is one of our initial storage projects globally on this scale using DC-coupling. Africa is a very promising market for energy storage due to relatively poor state grid infrastructure and high electricity price, there is a strong potential to replace peaker gas or cola fired plants in Africa with cleaner alternatives like solar made dispatchable using batteries,” said Gener Miao, CMO of Jinkosolar.

Photo – https://mma.prnewswire.com/media/1537317/Africa_Energy_Storage.jpg

Teachers asked to adapt to new trends in education

Ejisu-Abankro (Ash), – The Ghana National Association of Teachers (GNAT) has advised members to adapt to the new trends and transformation in education.

“All over the world, education is being changed to improve life, and every time a teacher has to find a way of acclimatizing to it,” Madam Gifty Apanbil, a Deputy General Secretary in charge of Professional Development, GNAT, noted.

She said the adoption of new skills and expertise as pertained to the emerging trends in the educational sector, especially the knowledge and use of Information and Communication Technology (ICT), had become a necessity.

This was needed for effective teaching and learning to promote quality educational delivery at all levels, Madam Apanbil observed.

She was addressing a close-out session of the maiden “GNAT/CTF ‘Nkabom’ Project Overseas in-Service Training Workshop”, at Abankro in the EJisu Municipality of the Ashanti Region.

The training was organized by GNAT with support from the Canadian Teachers Federation (CTF).

In all, 160 participating teachers were drawn from 20 districts in the Region, comprising headteachers, lower primary, kindergarten, and newly-posted teachers.

Under the ‘Nkabom’ Project, some topics have been designed for teachers serving in deprived and under-served areas, to improve their teaching skills and creativity for the development of education in their respective communities.

Additionally, an aspect of the project dubbed ‘The Beginning Teachers Mentorship’ is to help newly-posted teachers who have not served more than three years, to be abreast of the realities of the teaching profession.

It further seeks to equip both old and new teachers with the skills to mentor others.

Madam Apanbil said the Association, as a professional body, would make sure members were well equipped through knowledge acquisition to be able to deliver on their mandates effectively.

It would not relent in the efforts to providing continuous professional training for members, she assured.

The Deputy General Secretary called on the government to make resources available for the continuous development of teachers to build a resilient teaching force that would provide quality education for Ghanaian children.

She said the GNAT had planned to decentralize such training programmes for the benefit of all its members.

Madam Richarda Tandoh Appiah, the Regional Secretary of GNAT, urged the beneficiary teachers to share the knowledge acquired with other teachers in their respective schools.

She asked teachers to play pivotal roles in achieving the Sustainable Development Goal Four (SDG4), which aimed at ensuring inclusive and equitable education and promoting lifelong learning opportunities for all.

Source: Ghana News Agency

GES Director cautions students against deviant behaviours

AkyemWenchi (E/R) – Mr Thomas More Mensah Tsorhe, the District Director of Ghana Education Service (GES) in Denkyembour, has cautioned students to desist from deviant behaviours that hamper effective teaching and learning.

He said his outfit was poised for a holistic approach that augured a satisfactory academic performance and would therefore not entertain unpleasant acts from students.

The holistic approach introduced to improve academic performance include effective planning and management coupled with a student-friendly safe environment and monitoring.

The Director made this statement during the launch of the “Daasebre Awards” at Salvation Army Senior High School at AkyemWenchi in the Denkyembour district of the Eastern region.

The Awards aim at motivating hard-working teachers to uplift the academic standard of the school.

Mr Isaac Owusu Agyeman, the Headmaster of Salvation Army Senior High School – AkyemWenchi, said the school established in 1991 with 12 students, has had its population increased to 1,446 in 2021 with 63 teaching staff and 59 non-teaching staff.

He, therefore, appealed for the completion of a girls’ dormitory, two classroom blocks, an ultra-modern toilet facility, and an administration block.

In a response to the appeal for completion of the aforementioned projects, Mr Seth Birikorang, District Chief Executive of the Denkyembour, said measures were underway by the government for their completion.

Students who spoke with the GNA on condition of anonymity raised concern about insecurity in the school, citing instances of unauthorised movement of motors and tricycles on the school compound.

The situation, according to the students, at times leads to violent confrontations between the students and the riders.

They appealed to the government and benevolent organisations for the walling or fencing of the school to ward off criminals.

Source: Ghana News Agency

Geodrill donates generously towards Achimota Schools science lab complex

The CEO of Geodrill Mr. David Harper, presented a large cheque for GHS150,000 to the Old Achimotan Association (OAA) at a ceremony held June 14. The amount is Geodrill’s contribution towards the equipping and use of Achimota School’s state of the art science laboratory complex by the current and future students of the school.

The cheque was gratefully received by the president of the OAA and former Vice Chancellor of the University of Ghana, Professor Ernest Aryeetey. Also present at the presentation ceremony were some alumni of the school, the Headmistress, teachers and students.

Mr. Harper emphasised the importance of education to the students present and he expressed his hope that their education at Achimota School, and particularly in science, would set them on the path to successful adult careers and to contribute meaningfully to the development of Ghana.

Mr. Harper revealed a longstanding association with the school where he used to play cricket. He encouraged other companies to take their ESG obligations seriously and support worthy institutions to fulfil their mission. Geodrill, a leading drilling exploration company to the mining sector, is committed to being a socially responsible company that actively promotes social causes such as the education of Ghanaian youth. The support for the laboratory complex is yet another purposeful outcomes-based Geodrill ESG initiative.

According to Prof Aryeetey, the science lab was constructed with the support of corporate sponsors, who contributed about one-third of the total cost, and the remainder from Achimota alumni. The OAA and Achimota were still hopeful of receiving further contributions from other companies to sustainably fund the provision of science education and other programmes for the benefit of the students.

Prof. Aryeetey gave Mr. Harper a tour of the science laboratory complex after the presentation ceremony.

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Source: Ghana Web

CSIR College of Science and Technology inaugurates Alumni Association

Femesua (Ash), – A six-member National Executive of CSIR College of Science and Technology (CCST) Alumni Association has been inaugurated with a call on them to mobilise graduates of the college to serve as good ambassadors.

As the first National Executives of the Association, they were tasked to equip stakeholders in the physical and natural sciences with the appropriate skills and attitude to enhance their contribution to sustainable development in Ghana and beyond.

Prof. Moses B. Mochiah, Director for CSIR-CRI and the Representative of CSIR Director on the Board of the CCST, said the alumni represented the most valuable asset and the permanent members of the CCST family.

He said the Alumni should be role models to students and support them with scholarships to enhance the learning ability of students in the College.

“We want you to be learning judges, coaches, business partners, internship providers, and college members,” he encouraged the Association.

He charged the Association to organize regular social events such as fun games and dinner dances for former students to maintain their connection with the college.

Prof. Mark Appiah, President of CCST who sworn the executive into office, said the college was committed to providing a quality learning environment and training that supports the development of appropriate skills needed for job placement.

“Unfortunately for many university graduates in Ghana, unemployment remains the biggest problem. Most graduates find it difficult to transition from university education to work mainly because of mismatch of skills required on the job market,” he pointed out.

This, he said, was because many university graduates did not have the skills to meet the needs of the labour market basically because university education had not been linked to the needs of the important sectors of the economy.

He further stated that “with the shrinking public sector employment opportunities, university education must be relevant by ensuring that education systems and programmes can equip students with the relevant skills for industry and other private-sector jobs.”

He said he would count on the CCST Alumni Association to support the college to train and send out graduates who would have exceptional skills needed by industry and the private sector.

Mr Charles Brefo- Nimo, the President of CCST Alumni, said the Association would spare time and a resource to raise the flag of the college to a greater height, saying it was a call to duty and service.

“I am confident that together we shall make this university proud by our exploits in the country and beyond. In the days ahead our alumni association would focus on our future together with the university administration and the governing board to lift the image and visibility of this noble university,” he pledged.

The executives are Charles Yaw Brefo-Nimo, President, Louisa Abena Ebbah, Vice President, Kwaku Osei Adu Agyeman, General Secretary, Eunice Okyere Agyapong, Organizer, Alexander Owusu Ansah, Treasurer and Agnes Achiaa Aboagye, Communication and Public Relations.

The CCST was established out of the research and development experiences of the Council for Scientific and Industrial Research (CSIR) to increase the scientific capacity needed to drive Ghana’s socio-economic development in line with CSIR mandate to expand the platform for science and technological application.

Source: Ghana News Agency

Bediako residents appeal to GWCL to resolve water crisis

Kpone, – Residents of Bediako, in Kpone-Katamanso Municipality have appealed to Ghana Water Company Limited (GWCL) to resolve the water crisis in the community.

They claimed that for about a month now, there had not been any flow of water through their pipes adding that the situation had forced most of them to buy water from people drawing water from unknown sources.

According to them, the problem begun after the construction of the railway line through the community.

The residents of Bediako made this known during a community durbar in the Nmlitsakpo Electoral Area, which was addressed by the Assembly Member of the area, Mr Isaac Newtown Tetteh.

Mr Tetteh reacting to the issue said he went to the railway site and realized some pipelines were damaged in the process of construction of the railways, claiming that the workers had filled the pipes with concrete which had blocked the flow of the water through the pipes for almost a month now.

The Assemblyman said he made efforts to get the Ghana Water Company Limited to repair the pipelines, but still they had not been any attempt to deal with the issue till now.

“I sent a letter to the District Office to notify them of the issue, but nothing had been done about it yet, I’ve called several times and they tell me they will be coming to the place to repair the pipelines, their responses are that they’ll come and do it,” he said.

Source: Ghana News Agency

Withdraw petition against Ayine – NDC

Accra, – The National Democratic Congress (NDC) has asked Chief Justice Kwasi Anin-Yeboah to withdraw a petition filed with the General Legal Council against Dr Dominic Ayine for alleged derogatory comments he made on the 2020 presidential election petition.

The comments followed a similar one made by Dr Ayine who was a former Deputy Attorney-General, which cast a slur on the administration of justice, where he eventually appeared before the Supreme Court and apologized for his conduct.

The Party said Dr Ayine’s views about the independence of the Judiciary were, views he was entitled to in line with his freedom of expression guaranteed under the 1992 Constitution, thus his invitation to appear before the Council, was allegedly an act of intimidation.

Mr Johnson Asiedu Nketia, the General Secretary of the NDC, said this at a press conference by the Party in Accra on Monday.

He said the NDC shared in the opinion expressed by Dr Ayine, adding the allegation that, the opinion was not “actionable and does not violate any rule or professional conduct rules for lawyers”, saying, “…Neither Dr Ayine, nor we in the NDC can be compelled to increase our confidence in the independence of the Judiciary even when the Court has not given us any basis or reason to do so.”

The General Secretary said the Party was concerned about the “seeming judicial dictatorship that is fast festering under the leadership of the current Chief Justice,” adding, “…Justice emanates from the people and is administered on our behalf. Public confidence in the independence of the Judiciary must therefore be earned and not forced on us.”

Mr Nketia said the Judiciary, like Parliament and the Executive, was not above criticism and that the country’s progressive march as a constitutional democracy would allegedly suffer a grave setback if the Disciplinary Committee of the council proceeded to hold an inquiry into the matter of Dr Ayine’s comment on the election petition after he had earlier appeared before the Supreme Court and apologized for denigrating the court during the election petition trial.

“Our Constitution and laws protect the integrity and independence of the Judiciary and not the sensibilities of judges. Judicial vanity is a threat to justice and must not be countenanced in any democracy”, he said, adding that, “We, therefore, join well-meaning Ghanaians to demand that the Chief Justice withdraws his petitions against Dr Ayine.”

Mr Nketia said they would continue to “defend the cause of freedom and of right”.

Source: Ghana News Agency